Udo Erasmus, pioneer of essential fatty acids, EFA's, omega-3, omega fats, Udo's Choice, Udo's Oil, cold-pressed flax-seed oil, trans-fats, Trans Fatty acids
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CLA - Conjugated or Compromised?

 

PART 5: Human Studies


Compared with Animal Studies, Human studies with CLA are far fewer and less impressive. Here they are:



 


  • 3.9g/day of CLA for 63 days did not show benefits regarding the prevention of atherosclerosis; blood cholesterol and lipoprotein levels did not change;42
  • 3.9g/day of CLA for 63 days did not show benefits regarding blood coagulation and platelet function;43
  • Increasing CLA in the fetus correlated with decreased length of gestation;44
  • 3.9g/day of CLA for 63 days did not show benefits regarding immune function in human females;45
  • 4.2g/day of CLA increased lipid peroxidation in men with abdominal obesity after one month of use;46
  • In patients with chronic renal failure, CLA did not help;47
  • At 3 g/day, CLA resulted in no fat loss, no change in appetite, no change in blood glucose, but increased insulin and produced a transient decrease in leptin; CLA did not affect these parameters in a manner that promotes fat loss;48
  • At 3 g/day, CLA provided no change in body composition, energy expenditure, fat oxidation, or respiratory exchange ratio;49
  • 4.2 g/day of CLA increased lipid peroxidation, apparently by both enzymatic and non-enzymatic processes;50 3.4 g/day of CLA reduced body fat mass; more than 3.4 g/day did not provide any additional benefit;51
  • 16 g/day of omega-6 LA from safflower oil did not result in any increase in CLA in the body, i.e. the human body does not make CLA from LA;52

 
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