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Lungs
Ann Intern Med 1985 Dec;103(6 ( Pt 1)):883-5
Effects of low and high carbohydrate feedings
in ambulatory patients with chronic obstructive pulmonary disease and
chronic hypercapnia. |
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| Angelillo
VA, Bedi S, Durfee D, Dahl J, Patterson AJ, O'Donohue WJ Jr. |
| In
a randomized, double-blinded study, patients with chronic obstructive
pulmonary disease and hypercapnia were fed low, moderate, and high
carbohydrate diets to determine the effect on metabolic and ventilatory
values. The low carbohydrate diet consisted of 28% carbohydrate
calories and 55% fat calories and resulted in significantly lower
production of CO2 (p less than 0.002), respiratory quotient (p
less than 0.001), and arterial Pco2 (p less than 0.05). At the
end of the 15-day study, both the forced vital capacity (p less
than 0.05) and the forced expiratory volume in 1 second (p less
than 0.05) had improved by 22% over baseline values. Total calories
given surpassed daily caloric requirements. This approach, together
with a low carbohydrate, high fat mixture, may be beneficial for
such patients. |
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| PMID:
3933397 [PubMed - indexed for MEDLINE] |
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