Ingredients
The substances discussed in this section—presented in alphabetical order—are the most important dietary ingredients shown to attenuate, or slow, the aging process. Their use as a means of nutritional supplementation is crucial not only for delaying these processes, i.e., increasing the health-span, but possibly for increasing the life-span of humans as well—a thesis which is as yet unproven in humans, but is supported by considerable animal research. Effective levels of all of the following ingredients are contained in TimeGuard.™
As you review this section, keep in mind what you’ve learned about the principal factors contributing to premature aging—the Causes of Aging—and how the strategies discussed below are useful in attenuating these previously-enumerated processes: 1) glycation, lipoxidation, and carbonylation, 2) immune system dysfunction, 3) unhealthy inflammatory response, 4) mitochondrial energy depletion, 5) free radical oxidation, 6) periodic stress, and 7) accumulation of environmental pollutants.
Acetyl-L-Carnitine
Carnitine, also known as L-carnitine, is a naturally-occurring compound synthesized within the body from the amino acids lysine and methionine. Acetyl-L-carnitine (ALCAR) is the acetylated (slightly altered chemical ester) variety of carnitine, which is believed to be a more effective form of the substance. ALCAR has recently been shown to restore several important functions relating to mitochondrial health and efficiency. Read more >>>
Benfotiamine
Developed in Japan in the late 1950s, benfotiamine has been marketed in Japan since 1962, in Europe since 1992 and in the U.S. since 2005. It is a slightly altered derivative of vitamin B1, thiamine. Unlike thiamin which is water soluble, benfotiamine is fat soluble, allowing it easier access into cells in comparison to its water-soluble counterpart. Read more >>>
Carnosine
The word “protein” is derived from the Greek word “prota,” which means “of primary importance.” Protein constitutes one of the basic macromolecular building blocks of the body, and is assembled from amino acids which are either synthesized by the body or uptaken through the diet. Proteins are essential components within the cells of all living organisms, and play vital roles in various bodily functions including immunity, enzyme catalysis, cell signaling, skeletal structure, and metabolism. (See Free Radical Oxidation section for a further discussion of proteins.) Read more >>>
Co-Enzyme Q10
All living things contain complex protein substances called enzymes. Within the human body, enzymes initiate and moderate chemical reactions either to create molecular structures or to produce the electrochemical energy which powers the body’s cellular engines. Enzymes are composed of at least two ingredients: a protein component and a cofactor component. The protein component consists of specific amino acids which are determined by the genetic code. The cofactor component consists either of mineral ions (e.g., magnesium, calcium and zinc), vitamins, or sometimes both. The vitamin component of the cofactor is typically referred to as a coenzyme. [1] Read more >>>
DMAE & PABA
During the late 1940s, Romanian cardiologist Dr. Ana Aslan pioneered the use of injectable procaine hydrochloride—a drug—in the treatment of geriatric patients. She discovered inadvertently that procaine—also called Novocaine,® a local anesthetic—not only acts as an analgesic (pain killer), it provides many additional health benefits as well. For decades Dr. Aslan was the director of the National Institute of Gerontology and Geriatrics in Romania, where she dedicated herself to discovering the medical benefits of procaine. Read more >>>
Glutathione
It has been estimated that up to 75% of detoxification activity takes place in the liver,1 the human body’s second largest organ—the skin being the largest. Within the liver, the conversion of undesireable pollutants into forms able to be eliminated entails complex chemical processes. The detoxification process consists of two distinct phases, each involving a battery of enzymes. [2] Read more >>>
Resveratrol
Of the various substances investigated as possible calorie restriction mimetics, one stands out as a leader—resveratrol, a substance first identified as recently as the early 1980s. A naturally-occurring compound, resveratrol is found in various food-stuffs and plants including berries, grapes, peanuts, pine trees, some herbs, and most notably in the root of the plant Polygonum cuspidatum. It occurs in a cis and trans molecular form, the trans form being biologically active. Read more >>>
ADDITIONAL INGREDIENTS:
Commentary on the above ingredients was written by Guardian Therapeutics’ in-house staff, largely using peer-reviewed articles as resource material. For a discussion of the following ingredients—also contained in TimeGuard™—we take you off site to read other researchers’ commentary on the following ingredients: